BLUHM CARDIOVASCULAR INSTITUTE

Revolution in Transcatheter Heart Valve Therapies

As one of the highest volume and most experienced transcatheter aortic heart valve replacement (TAVR) programs in the nation, Northwestern Medicine continues to expand its Transcatheter Heart Valve Program by offering a wide array of commercially available and clinical trials for the aortic, mitral and tricuspid valves.

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Setting the Pace for Transcatheter Heart Valve Therapies

The Transcatheter Heart Valve Program at Northwestern Medicine offers a wide variety of commercially available (FDA approved) and clinical trial options for the aortic, mitral and tricuspid valves, allowing us to tailor treatment precisely to each patient’s individual needs.

The Transcatheter Heart Valve Program continues to grow, not only in therapies offered but also in locations. In addition to a number of transcatheter heart valve therapies being offered at Northwestern Memorial Hospital, transcatheter aortic valve therapy (TAVR) is now available at Central DuPage Hospital.

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Meet the Team

Bluhm Cardiovascular Institute at Northwestern Memorial Hospital
 675 N. Saint Clair Street
 Galter Pavilion, Suite 19-100
 Chicago, IL 60611
312.NM.HEART (312.664.3278)

Charles J. Davidson, MD 
 Interventional Cardiology
Procedures performed: TAVR, Aortic Valve in Valve, Mitral Valve in Valve, MitraClip
Research studies: ACTIVE, Apollo, Cardioband TR, COAPT CAS, EARLY TAVR, EXCEED, MitraClip EXPAND, PARTNER 3 CAP, PARTNER 3 Aortic Valve in Valve, PARTNER 3 Mitral Valve in Valve 
 

James D. Flaherty, MD 
 Interventional Cardiology
Procedures performed: TAVR, Aortic Valve in Valve, Mitral Valve in Valve
Research studies: ACTIVE, EARLY TAVR, EXCEED, PARTNER 3 CAP, PARTNER 3 Aortic Valve in Valve, PARTNER 3 Mitral Valve in Valve
 

Transcatheter heart valve therapies are minimally invasive procedures to repair or replace a diseased heart valve that involves threading a catheter (tube) through a small incision made in the skin. The device needed to repair or replace the diseased valve is placed in the lumen of the catheter and feed through an artery in the body until it reaches the diseased heart valve. 

Transcatheter heart valve therapies offer some people an alternative to open heart valve surgery. Transcatheter therapies allow the procedure to be performed while the patient’s heart is still beating, eliminating the need for a “bypass” machine and its associated risks. Transcatheter heart valve therapies are an especially important treatment option for people considered high risk for open heart valve surgery. 

Transcatheter Heart Valve Procedures

Mitral Valve Transcatheter Treatment Options

MitraClip: commercially available
 A minimally invasive treatment option for patients with mitral regurgitation who are too high risk for open heart valve surgery. With mitral regurgitation the mitral valve does not close completely, allowing blood to flow backward or “leak,” creating symptoms that may include shortness of breath, fatigue and chest pain. 
 

The MitraClip device is inserted in to the body through a catheter (tube) placed in the patient’s femoral (groin) vein. Once in the heart, the device is positioned and placed to join or “clip” together a portion of the mitral valve, reducing or eliminating the backward flow of blood. 

Mitral Valve in Valve Replacement: commercially available 
A minimally invasive transcatheter mitral valve replacement (TMVR) procedure for patients who have had previous open heart valve surgery to replace the mitral valve with a bioprosthetic/tissue valve and the tissue valve is now failing. Instead of the failing mitral valve being replaced during another open heart valve surgery, the failing mitral tissue valve is replaced by placing a TMVR valve inside the failing mitral tissue valve. 

Mitral Valve Transcatheter Clinical Trials:
COAPT CAS, offered at Northwestern Memorial Hospital for select patients with mitral valve regurgitation – enrolled subjects receive the study device
MitraClip EXPAND, offered at Northwestern Memorial Hospital for select patients with mitral valve regurgitation 
PARTNER 3 Mitral Valve in Valve, offered at Northwestern Memorial Hospital for patients with a failing mitral bioprosthetic valve 
Apollo, offered at Northwestern Memorial Hospital for select patients with mitral valve regurgitation  

MitraClip in place clipping together a portion of the mitral valve

Aortic Valve Transcatheter Treatment Options

TAVR valve shown in aortic valve position

Tricuspid Valve Transcatheter Treatment Options

Mark J. Ricciardi, MD 
 Interventional Cardiology
Procedures performed: TAVR, Aortic Valve in Valve, Mitral Valve in Valve, MitraClip
Research studies: ACTIVE, Apollo, Cardioband TR, COAPT CAS, EARLY TAVR, EXCEED, MitraClip EXPAND, PARTNER 3 CAP, PARTNER 3 Aortic Valve in Valve, PARTNER 3 Mitral Valve in Valve
 

Ranya N. Sweis, MD 
 Interventional Cardiology
Procedures performed: TAVR, Aortic Valve in Valve, Mitral Valve in Valve
Research studies: COAPT CAS, EARLY TAVR, EXCEED, PARTNER 3 CAP, PARTNER 3 Aortic Valve in Valve, PARTNER 3 Mitral Valve in Valve
 

S. Chris Malaisrie, MD 
 Cardiac Surgery
Procedures performed: TAVR, Aortic Valve in Valve, Mitral Valve in Valve
Research studies: ACTIVE, Apollo, Cardioband TR, COAPT CAS, EARLY TAVR, EXCEED, MitraClip EXPAND, PARTNER 3 CAP, PARTNER 3 Aortic Valve in Valve, PARTNER 3 Mitral Valve in Valve
 

Andrei Churyla, MD 
 Cardiac Surgery
Procedures performed: TAVR, Aortic Valve in Valve, Mitral Valve in Valve 

Research Studies: EXCEED, PARTNER 3 Mitral Valve in Valve 

Duc Thinh Pham, MD 
 Cardiac Surgery
Procedures performed: TAVR, Aortic Valve in Valve, Mitral Valve in Valve
Research studies: EARLY TAVR, EXCEED, PARTNER 3 CAP, PARTNER 3 Aortic Valve in Valve, PARTNER 3 Mitral Valve in Valve
 

Bluhm Cardiovascular Institute at Central DuPage Hospital
25 N. Winfield Road
Winfield, IL 60190
630.232.0280

Imran N. Ahmad, MD 
 Interventional Cardiology
Procedures performed: TAVR 
 

Gyu I. Gang, MD 
 Cardiac Surgery
Procedures performed: TAVR
 

Contact Us 
 For more information regarding transcatheter heart valve therapies, please contact:

 Bluhm Cardiovascular Institute at Northwestern Memorial Hospital 312.NM.HEART (312.664.3278) 
 or
 Bluhm Cardiovascular Institute at Central DuPage Hospital 630.232.0280 

Aortic valve in valve replacement

Northwestern Memorial Hospital 312.NM.HEART (312.664.3278)Central DuPage Hospital 630.232.0280

Mitral valve in valve replacement

We are proud of our U.S. News & World Report rankings - a reflection of the leading-edge cardiac and vascular services we offer and the results we achieve for our patients, their families and the region we serve. 

  • No. 1 in Illinois for 11 consecutive years
  • No. 7 in the nation out of 613 cardiology and heart surgery programss
  • Highest ranked cardiovascular program in the region: Indiana, Michigan, Wisconsin, Missouri and Iowa

Patrick M. McCarthy, MD 
 Cardiac Surgery
Research Studies: Apollo
 

Transcatheter Aortic Valve Replacement (TAVR): commercially available
 A minimally invasive treatment option for patients with aortic valve stenosis. A stenotic aortic valve is narrowed, restricting blood flow from the heart. The TAVR valve is compressed and fed by a catheter (tube) through an artery in the groin (transfemoral approach) or a small incision between the ribs (transapical approach) until it reaches the diseased aortic valve. A balloon expands or wedges the TAVR valve within the patient’s diseased aortic valve and the catheter is removed. The TAVR valve remains in place pushing the diseased valve out of the way, allowing the TAVR valve to take over the job of regulating blood flow. 
 

Aortic Valve in Valve Replacement: commercially available
 A minimally invasive TAVR procedure for patients who have had previous open heart valve surgery to replace the aortic valve with a bioprosthetic/tissue valve and the tissue valve is now failing. Instead of the failing aortic tissue valve being replaced during another open heart valve surgery, the failing aortic tissue valve is replaced by placing a TAVR valve inside the failing aortic tissue valve. 
 

Aortic Valve Transcatheter Clinical Trials: 
PARTNER 3 CAP, offered at Northwestern Memorial Hospital for select patients at low risk for surgical aortic valve replacement – enrolled subjects receive the study device 
PARTNER 3 Aortic Valve in Valve, offered at Northwestern Memorial Hospital for patients with a failing aortic bioprosthetic valve 
EARLY TAVR, offered at Northwestern Memorial Hospital for patients with asymptomatic severe aortic stenosis 
EXCEED, offered at Northwestern Memorial Hospital select patients at intermediate risk for surgical aortic valve replacement  

Tricuspid Valve Transcatheter Clinical Trials:
Cardioband, offered at Northwestern Memorial Hospital for select patients with tricuspid valve regurgitation  

Jonathan Tomasko, MD 
 Cardiac Surgery
Procedures performed: TAVR 
 

Nauman Mushtaq, MD 
 Interventional Cardiology
Procedures performed: TAVR